An eight-game NBA schedule tips off the new week, and one of Sunday’s featured contests is a meeting between the Portland Trail Blazers and the OKC Thunder, two of the league’s most promising young squads. This marks the second showdown between the teams this season; Portland won the first matchup 121-119, handing the Thunder their lone loss of the year so far. Thanks for the submission! Here’s a preview of this season’s second Portland Trail Blazers vs OKC Thunder game, scheduled to tip off at 7 p. m. ET at Paycom Center in Oklahoma. 70% Win (110-25-1) 70% Win (110-25-1) 70% Win (110-25-1) Unlock Free tips from our Experts Get Picks Now Portland Trail Blazers vs OKC Thunder Preview and Odds Moneyline: Blazers (+687) vs Thunder (-1200) Spread: Blazers +15. 5 (-110) vs Thunder -15. 5 (-110) Total (O/U): Kings o234. 5 (-110) vs Thunder u234. 5 (-110) Editor’s note: The odds could change close to the game. The odds listed were as per available information at the time of writing. Portland Trail Blazers vs OKC Thunder preview After Portland beat the Thunder on Nov. 5 to move to 5-3, the team has largely struggled, dropping six of its last eight games. Now sitting at 7-9, the Blazers meet an OKC squad eager to even the season series. Portland’s 121-119 victory in that first outing came after erasing a 22-point hole to shock the defending champions. Since then, the Thunder have rattled off eight straight wins and currently hold a league-best 16-1 record. In that initial matchup, the Thunder were missing Alex Caruso, Kenrich Williams, Chet Holmgren and Jalen Williams. For this game, both Williamses remain sidelined along with Aaron Wiggins. Portland entered the first meeting mostly healthy, but they’ll now be without Jrue Holiday, Shaedon Sharpe, Matisse Thybulle, Blake Wesley, Robert Williams III and Scoot Henderson. Donovan Clingan is listed as questionable. Every Thunder win since their loss to Portland has come by double digits. The Blazers have hovered around the middle of the league statistically, ranking 16th in offensive rating and 21st in defensive rating, while the Thunder own the NBA’s top defensive and net ratings. Portland Trail Blazers vs OKC Thunder betting tips Shai Gilgeous-Alexander O/U 32. 5 points Take the over. Deni Avdija O/U 25. 5 points Take the under. Chet Holmgren O/U 17. 5 points Take the over. Toumani Camara O/U 14. 5 points Take the over. Portland Trail Blazers vs OKC Thunder prediction The Thunder should be in control throughout, especially with Portland missing so many key pieces. Expect the Blazers’ defense to compete early, but OKC should pull away comfortably, essentially the opposite of what happened in the first meeting. Our prediction: Thunder win by 16.
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Portland Trail Blazers vs OKC Thunder Prediction and Betting Tips – Nov. 23 | 2025-26 NBA Season

